The Endoplasmic Reticulum Stress Response in Neuroprogressive Diseases: Emerging Pathophysiological Role and Translational Implications
Molecular Neurobiology, pp. 8765-8787, 2018.
NeurodegenerationNeuroprogressionUnfolded protein responseMood disordersEndoplasmic reticulum stressMore(1+)
The endoplasmic reticulum (ER) is the main cellular organelle involved in protein synthesis, assembly and secretion. Accumulating evidence shows that across several neurodegenerative and neuroprogressive diseases, ER stress ensues, which is accompanied by over-activation of the unfolded protein response (UPR). Although the UPR could initi...More
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