The antiviral activity of arbidol hydrochloride against herpes simplex virus type II (HSV-2) in a mouse model of vaginitis.
International Immunopharmacology(2019)
摘要
•ARB showed anti-HSV-2 activity in vitro in a dose-dependent manner.•ARB inhibited the late replication cycle of HSV-2.•ARB ointment participated in the regulation of immune response to reduce the reproductive tract injury.•ARB in ointment form responded to vaginitis better than in oral form.
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关键词
Arbidol hydrochloride,HSV-2,Mechanism of action,In vitro,In vivo
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