Effects of long noncoding RNA (linc-VLDLR) existing in extracellular vesicles on the occurrence and multidrug resistance of esophageal cancer cells.

YueTong Chen,Liang Liu,Jie Li,Yu Du,Jing Wang,JiangHui Liu

Pathology - Research and Practice（2019）

引用 28|浏览3

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摘要

High expression of Linc-VLDLR and ABCG2 gene in esophageal cancer cells affected the formation of esophageal cancer drug resistance. EVs released by drug-resistant cells were proved that they could upregulate the expression of ABCG2 in esophageal cancer cells and thus regulate the drug resistance of esophageal cancer cells, which was related to the linc-VLDLR carried by EVs.

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关键词

Esophageal neoplasms,Extracellular vesicles,Long noncoding RNA,Multidrug resistance,ATP binding cassette G2

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