In Vitro Neutralization Assay Using Cultured Hepatitis C Virus

    Jannick Prentoe
    Jannick Prentoe

    Methods in molecular biology (Clifton, N.J.), Volume 1911, 2019, Pages 433-439.

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    Keywords:
    AntibodiesHCVHepatitis C virusImmunostainingNeutralizationMore(1+)

    Abstract:

    The method outlined here enables evaluation of the neutralization potency of monoclonal and polyclonal antibodies against in vitro cultured hepatitis C virus (HCV). The high variation in envelope protein sequence among HCV isolates necessitates the inclusion of several isolates, spanning the major genotypes of HCV, in order to make strong...More

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