The immunotherapeutic effects of recombinant Bacillus Calmette-Guérin resistant to antimicrobial peptides on bladder cancer cells.

•Our rBCG strains evade the action of AMPs and show enhanced internalization in bladder cancer cells.•The rBCG strains increase the secretion of anticancer cytokines.•The rBCG strain can improve the efficacy of BCG as a treatment for bladder cancer.