Prognostic significance of circulating tumor cells (CTCs) in Egyptian non-metastatic colorectal cancer patients: A comparative study for four different techniques of detection (Flowcytometry, CellSearch, Quantitative Real-time PCR and Cytomorphology).

Abeer A Bahnassy,Salem E Salem,Marwa Mohanad, Nermeen Z Abulezz,Mona S Abdellateif,Marwa Hussein,Chahd A N Zekri,Abdel-Rahman N Zekri,Nasr M A Allahloubi

Experimental and Molecular Pathology（2019）

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摘要

Enumeration of CTCs by FCM and RNA expression for specific colon cancer markers are comparable to CS regarding sensitivity and specificity. CTCs also represent novel therapeutic targets for NMCRC cases.

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关键词

Circulating tumor cells count,mRNA markers,Non-metastatic colorectal cancer,Early detection,Prognosis

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