Needs and Challenges for Radiation Oncology in the Era of Precision Medicine.

Precision radiation oncology necessitates the systematic curation of clinically relevant heterogeneity at the patient, disease state and treatment level, in turn, relating these measures to the longitudinal health outcomes of the irradiated cancer patient to gain personalized prediction and therapeutic insights. Leveraging the database and imaging platforms intrinsic to characterizing the heterogeneity of radiation therapy to develop an effective informatics infrastructure amongst a network of institutions is a critical goal to realize precision radiation oncology.