Data Highlighting The Expression Of Two Mir-132/212 Target Genes-Sirt1 And Pten-After Chronic Stress

DATA IN BRIEF(2018)

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摘要
The data presented here are related to our research article entitled "miR-132/212 is induced by stress and its dysregulation triggers anxiety -related behavior" (Aten et al., 2018). In this article, we utilize immunofluorescent techniques to examine the protein level expression of two microRNA-132/212 target genes, Sirt1 and Pten, in miR-132 transgenic and miR-132/212 conditional knockout (cKO) mouse lines. Additionally, using immunohistochemistry, we detail the expression profile of Sirt1 and Pten in the hippocampus and amygdala of WT mice after a 15 day chronic restraint stress paradigm. (C) 2018 The Authors. Published by Elsevier Inc.
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关键词
NGS,Normal Goat Serum,TRE,tetracycline-regulated element,WT,wild-type,cKO,conditional knockout,miR,microRNA
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