In vivo transcriptome changes of human white blood cells in response to vitamin D.

Antonio Neme,Sabine Seuter,Marjo Malinen,Tarja Nurmi,Tomi-Pekka Tuomainen,Jyrki K Virtanen,Carsten Carlberg

The Journal of Steroid Biochemistry and Molecular Biology（2019）

引用 46|浏览21

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摘要

•In human PBMCs 702 genes are significantly (p < 005) affected by a vitamin D3 bolus.•These genes are involved in general protein translation, monocyte differentiation and cellular growth control.•The expression pattern of vitamin D target genes differed significantly between individuals.

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关键词

1,25(OH)2D3,25(OH)D3,BMI,FC,FE,HLA,KEGG,MHC,PBMC,RNA-seq

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