Inhibition of autophagy by chloroquine makes chemotherapy in nasopharyngeal carcinoma more efficient.

Tomomi Aga,Kazuhira Endo,Akira Tsuji,Mitsuharu Aga,Makiko Moriyama-Kita,Takayoshi Ueno,Yosuke Nakanishi,Miyako Hatano,Satoru Kondo,Hisashi Sugimoto,Naohiro Wakisaka,Tomokazu Yoshizaki

Auris Nasus Larynx（2019）

引用 13|浏览7

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摘要

These results suggest that autophagy, represented by Beclin 1, is upregulated after chemotherapy in both in vitro and in vivo NPC studies. Inhibition of autophagy could therefore be new strategy for NPC treatment.

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关键词

Autophagy,Beclin 1,Chloroquine,LC3,Nasopharyngeal carcinoma

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