A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer

Rosanna M Robertson,Jiangwei Yao,Stefan Gajewski,Gyanendra Kumar,Erik W Martin,Charles O Rock,Stephen W White

NATURE STRUCTURAL & MOLECULAR BIOLOGY（2017）

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摘要

The crystal structure of Thermotoga maritima lysophosphatidic acid acyltransferase reveals a two-helix motif that positions the active site for catalysis within the membrane bilayer.

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关键词

Membrane lipids,Membrane proteins,Transferases,X-ray crystallography,Life Sciences,general,Biochemistry,Protein Structure,Membrane Biology,Biological Microscopy

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