Draft Genome Sequences Of Three Actinobacteria Strains Presenting New Candidate Organisms With High Potentials For Specific P450 Cytochromes

Christian Grumaz,Yevhen Vainshtein,Philipp Kirstahler,Stephan Luetz,Matthias Kittelmann,Kirsten Schroer,Fabian K Eggimann,Rico Czaja,Andreas Vogel,Thomas Hilberath, Anne Worsch,Marco Girhard,Vlada B Urlacher, Marcel Sandberg,Kai Sohn

MICROBIOLOGY RESOURCE ANNOUNCEMENTS（2017）

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摘要

The three Actinobacteria strains Streptomyces platensis DSM 40041, Pseudonocardia autotrophica DSM 535, and Streptomyces fradiae DSM 40063 were described to selectively oxyfunctionalize several drugs. Here, we present their draft genomes to unravel their gene sets encoding promising cytochrome P450 monooxygenases associated with the generation of drug metabolites.

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