RACK1 forms a complex with FGFR1 and PKM2, and stimulates the growth and migration of squamous lung cancer cellsWOS
Molecular carcinogenesis, Volume 56, Issue 11, 2017, Pages 2391-2399.
Keywords:FGFR1PKM2RACK1cell growth and migrationlung cancer
Phosphorylation of Pyruvate Kinase M2 (PKM2) on Tyr105 by fibroblast growth factor receptor 1 (FGFR1) has been shown to promote its nuclear localization as well as cell growth in lung cancer. Better understanding the regulation of this process would benefit the clinical treatment for lung cancer. Here, it has been found that the adaptor p...More