Links between critical proteins drive the controllability of protein interaction networks

    Proteomics, 2017.

    Cited by: 7|Bibtex|Views8|Links
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    Keywords:
    Critical proteinsNetwork controlProtein-protein interactions

    Abstract:

    Focusing on the interactomes of Homo sapiens, Saccharomyces cerevisiae, and Escherichia coli, we investigated interactions between controlling proteins. In particular, we determined critical, intermittent, and redundant proteins based on their tendency to participate in minimum dominating sets. Independently of the organisms considered, w...More

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