Cynomolgus monkeys are successfully and persistently infected with hepatitis E virus genotype 3 (HEV-3) after long-term immunosuppressive therapy

    Juliana Rodrigues Guimarães
    Juliana Rodrigues Guimarães
    Juliana Gil Melgaço
    Juliana Gil Melgaço
    Yohan Britto Kevorkian
    Yohan Britto Kevorkian
    Fernanda de Oliveira Bottino
    Fernanda de Oliveira Bottino
    Aline Campos de Azevedo da Silva
    Aline Campos de Azevedo da Silva
    Laís Bastos da Fonseca
    Laís Bastos da Fonseca
    Leandro Schiavo Vilhena
    Leandro Schiavo Vilhena
    Edilson Uiechi
    Edilson Uiechi

    PloS one, Volume 12, Issue 3, 2017.

    Cited by: 7|Bibtex|Views0|Links
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    Abstract:

    Epidemiological studies found that hepatitis E virus genotype 3 (HEV-3) infection was associated with chronic hepatitis and cirrhosis in immunocompromised patients. Our study aimed to investigate the relationship between the host immunosuppressive status and the occurrence of HEV-related chronic hepatitis. Here we describe a successful ex...More

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