Pneumocystis pneumonia in patients with inflammatory or autoimmune diseases: Usefulness of lymphocyte subtyping.

Yi Li,Marc Ghannoum, Chuntao Deng,Yanxia Gao,Huadong Zhu,Xuezhong Yu,Valery Lavergne

International Journal of Infectious Diseases（2017）

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摘要

•Lymphocyte subtyping is useful for predicting Pneumocystis jirovecii pneumonia (PCP) and related mortality in non-HIV patients.•A CD3+ cell count <625×106/l was found to be an independent predictor and the strongest predictor of PCP.•90% of patients with PCP had a CD3+ cell count <750×106/l.•Low CD8+ was found to be an independent predictor and the strongest predictor of mortality in PCP patients.

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关键词

Lymphocyte subtype,CD3+ cell,CD8+ cell,Inflammatory disease,Autoimmune disease,Pneumocystis jirovecii

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