Involvement of histone methylation in macrophage apoptosis and unstable plaque formation in methionine-induced hyperhomocysteinemic ApoE -/- mice.

Guangzhi Cong,Ru Yan,Hui Huang,Kai Wang,Ning Yan,Ping Jin,Na Zhang,Jianjun Hou,Dapeng Chen,Shaobin Jia

Life Sciences（2017）

引用 21|浏览9

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摘要

Our data suggest that Hhcy promotes the progression of atherosclerosis via macrophage apoptosis. Histone methylation might be involved in macrophage apoptosis and unstable plaque formation in methionine induced hyperhomocysteinemic ApoE mice.

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关键词

Epigenomics,Atherosclerosis,Apoptosis,Histone methylation,Hyperhomocysteinemia

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