Serratia marcescens harboring SME-4 in Brazil: A silent threat.

Rodrigo Cayô,Rodrigo Cuiabano Paes Leme,Ana Paula Streling,Adriana Pereira Matos,Carolina Silva Nodari,Jessica Reis Esteves Chaves, Jorge Luiz Ferreira Brandão, Maíra Fernandes de Almeida, Valério Carrareto, Marco Aurélio de Castro Pereira, Jean Pierre Aquino de Almeida, Demian Candido Ferreira,Ana Cristina Gales

Diagnostic Microbiology and Infectious Disease（2017）

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摘要

The intrinsic polymyxin resistance displayed by Serratia marcescens makes the acquisition of carbapenemase encoding genes a worrisome event. This study report a SME-4-producing S. marcescens isolate causing septic shock in Brazil. The insertion of novel resistance determinants and their consequent spread in our territory is noteworthy.

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关键词

Class A carbapenemase,Serine carbapenemase,Enterobacteriaceae,Carbapenem resistance,Serratia,Septic shock,Catheter-related bloodstream infection

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