Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthmaWOS
EBioMedicine, Volume 152017, Pages 137-149.
Keywords:AsthmaEndoplasmic reticulum stressLyn kinaseMUC5ACMucus secretion
In asthma, mucus hypersecretion is thought to be a prominent pathological feature associated with widespread mucus plugging. However, the current treatments for mucus hypersecretion are often ineffective or temporary. The potential therapeutic targets of mucus hypersecretion in asthma remain unknown. Here, we show that Lyn is a central ef...More