Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthmaWOS

    Yin Li
    Yin Li
    Xi Dai
    Xi Dai
    Bin Niu
    Bin Niu
    Juan Wu
    Juan Wu
    Xiefang Yuan
    Xiefang Yuan
    Anjie Xiong
    Anjie Xiong
    Cited by: 15|Bibtex|12|

    EBioMedicine, Volume 152017, Pages 137-149.

    Keywords:
    AsthmaEndoplasmic reticulum stressLyn kinaseMUC5ACMucus secretion

    Abstract:

    In asthma, mucus hypersecretion is thought to be a prominent pathological feature associated with widespread mucus plugging. However, the current treatments for mucus hypersecretion are often ineffective or temporary. The potential therapeutic targets of mucus hypersecretion in asthma remain unknown. Here, we show that Lyn is a central ef...More
    Your rating :
    0

     

    Tags
    Comments