Myogenic potential of mouse embryonic stem cells lacking functional Pax7 tested in vitro by 5-azacitidine treatment and in vivo in regenerating skeletal muscle.

Anita Helinska,Maciej Krupa,Karolina Archacka,Areta M Czerwinska,Wladyslawa Streminska,Katarzyna Janczyk-Ilach,Maria A Ciemerych,Iwona Grabowska

European Journal of Cell Biology（2017）

引用 7|浏览14

暂无评分

摘要

•ESCs lacking Pax7 expressed higher levels of factors associated with myogenesis.•In vivo Pax7-/- ESCs more efficiently colonized skeletal muscle than control ones.•Differentiating Pax7-/- ESCs are more prone to initiate myogenic differentiation.

查看译文

关键词

ES cells,Myoblasts,Skeletal muscle,Differentiation,Pax7,5-azacitidine

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要