MicroRNA-29 facilitates transplantation of bone marrow-derived mesenchymal stem cells to alleviate pelvic floor dysfunction by repressing elastin.

Minfei Jin,Yuelin Wu,Jun Wang,Weiping Ye,Lei Wang,Peipei Yin,Wei Liu,Chenhao Pan,Xiaolin Hua

Stem cell research & therapy（2016）

引用 21|浏览10

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摘要

Our multidisciplinary study, combining microRNA biology, genetically engineered BMSCs, and nanoparticle technology, provides an excellent stem cell-based therapy for repairing connective tissues and treating PFD.

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关键词

Bone marrow-derived mesenchymal stem cells (BMSC),Elastin,MicroRNA-29a-3p,Nanoparticles,Pelvic floor dysfunction (PFD)

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