[Expert opinion about the use of transdermic oxybutynin in Spain for the treatment of adult overactive bladder.]

Carlos Müller-Arteaga,Salvador Arlandis Guzmán, María Fernanda Lorenzo Gómez,Carlos Errando-Smet, Raquel González López,Javier Cambronero Santos,José Luis Gutiérrez Baños, Manuel Sánchez Marcos, Antonio Ortiz Gamiz, Sergio Merino Salas, Roberto Martínez Rodriguez, Ivan Olano Grasa

ARCHIVOS ESPANOLES DE UROLOGIA(2016)

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摘要
OBJECTIVES: To define the different characteristics of transdermal oxybutynin (TO) for the treatment of overactive bladder in adults, to know the barriers for the use of this drug and to establish proposals to minimize these barriers. METHODS: Local sessions were held with 111 urologists from all over the country divided into 12 sessions. They were moderated by a brainstorming technique led by an external consultant. RESULTS: 75% of experts believe that tolerability and clinical efficacy (50%) are the most important attributes to choose this formulation, being the lack of scientific publications the least valued (12%). These opinions were based on their own clinical experience with TO or on scientific publications, without establishing comparison with other treatment options. The main barriers would be administrative obstacles (84%), difficulty in its use (54%) and the lack/rejection of the transdermal administration by the patient (33%). Actions were proposed to correct the 8 most significant barriers, such as better training for specialists (both Urology and other specialties) and for patients, creating informative materials to reinforce health education in managing patches, generating greater volume of scientific evidence to support their use in overactive bladder and clearly identifying the profile of patients who will benefit most from this therapeutic strategy. CONCLUSIONS: Although oxybutynin has been standard treatment of overactive bladder in recent years the conclusion of this working group is that its new transdermal formulation offers a better-tolerated alternative for patients, and, therefore the necessary tools to generate more evidence should be implemented to increase the proper use among specialists and patients.
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关键词
Urinary Bladder. Overactive [Mesh],Muscarinic Antagonists [Mesh],Transdermal Patch. [Mesh],Administration Cutaneous [Mesh],Oxybutynin [Supplementary Concept]
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