Intrathoracic neurogenic tumor with malignant transition-20 years operation experience in a medical center of China.

•The survival rate of malignant neurogenic intrathoracic tumors is related with tumor size, malignant degree and recurrence and incomplete resection.•The chemotherapy and radiation therapies are not effective, with poor prognosis.•The most effective treatment method for these tumors is early identification and resection by minimally invasive surgery during benign stage.