Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytesWOS

    Fei Gao
    Fei Gao
    Ningjie Ma
    Ningjie Ma
    Hong Zhou
    Hong Zhou
    Qing Wang
    Qing Wang
    Pu Wang
    Pu Wang
    Huan Wen
    Huan Wen
    Cited by: 0|Bibtex|9|

    International journal of nanomedicine, Volume 112016, Pages 3859-74.

    Keywords:
    ZnO nanoparticlecell cycle G2/M arresthistone modificationp53-Bax mitochondrial apoptosis pathwayreactive oxygen species

    Abstract:

    As an engineered nanomaterial, zinc oxide nanoparticles (ZnO NPs) are used frequently in biological applications and can make contact with human skin. Here, we systematically investigated the effects of ZnO NPs on non-tumorigenic human epidermal keratinocytes, which were used as a test model for this in vitro study, at the epigenetic and ...More
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