Alpha-Defensin 5 Expression is Regulated by microRNAs in the Caco-2 Intestinal Epithelial Cell Line.

Donald R B Miles, Jun Shen,Alice Y Chuang,Fenshi Dong,Feng Wu,John Kwon

Journal of inflammatory bowel diseases & disorders（2016）

引用 4|浏览13

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摘要

miR-124 and miR-924 negatively regulate DEFA5 mRNA and protein expression. These data implicate miRNAs in intestinal innate immune regulation and IBD pathogenesis.

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关键词

Defensin,Inflammatory bowel disease,MicroRNA regulation

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