Topical application of superoxide dismutase mediated by HIV-TAT peptide attenuates UVB-induced damages in human skin.

Xiaochao Chen,Shutao Liu,Pingfan Rao,Jeremy Bradshaw,Richard Weller

European Journal of Pharmaceutics and Biopharmaceutics（2016）

引用 16|浏览4

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摘要

•Topical application of superoxide dismutase can be enhanced by binding to HIV-TAT peptide.•TAT-SOD protein efficiently penetrated through the stratum corneum.•TAT-SOD protein significantly attenuated UVB-induced skin damage in man.

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关键词

UV,ROS,SOD,GFP,HIV,TAT,CPP,SC,MED,SBC

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