Antioxidant properties of thio-caffeine derivatives: Identification of the newly synthesized 8-[(pyrrolidin-1-ylcarbonothioyl)sulfanyl]caffeine as antioxidant and highly potent cytoprotective agent.

Beata Jasiewicz,Arleta Sierakowska, Natalia Wandyszewska,Beata Warżajtis,Urszula Rychlewska,Rafał Wawrzyniak,Lucyna Mrówczyńska

Bioorganic & Medicinal Chemistry Letters（2016）

引用 16|浏览5

暂无评分

摘要

C8-substitution of caffeine molecule by (pyrrolidin-1-yl)carbothioylsulfanyl group results in tremendous increase of antioxidant and cytoprotective in vitro activity of this novel, highly functionalized compound.

查看译文

关键词

Caffeine thioderivatives,Antioxidant activity,Haemolysis,Human erythrocytes,Trolox,X-ray structure

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要