Serum metabonomics study of anti-depressive effect of Xiao-Chai-Hu-Tang on rat model of chronic unpredictable mild stress.

Zhili Xiong,Jie Yang,Yue Huang,Kuo Zhang,Yunhai Bo,Xiumei Lu,Guangyue Su,Jie Ma,Jingyu Yang,Longshan Zhao,Chunfu Wu

Journal of Chromatography B（2016）

引用 37|浏览10

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摘要

•The potential biomarkers in a chronic unpredictable mild stress model were identified.•Nine metabolites were characterized as potential biomarkers.•The therapeutic effect of XCHT on depression relies on regulating various metabolic pathways.

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关键词

XCHT,CUMS,UPLC,QC,RT,RSD,RE,5-HT,ROS,RNS,LPC

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