Induction Immunosuppressive Therapy With Everolimus and Low-Dose Tacrolimus Extended-Release Preserves Good Renal Function at 1 Year After Kidney Transplantation.

•Patients using an induction immunosuppressive protocol of everolimus, low-dose tacrolimus extended-release, mycophenolate mofetil, prednisolone, and basiliximab developed subclinical rejection after 3 months at a significantly higher rate than those patients using a conventional protocol.•The findings of subclinical rejection disappeared after 1 year with administration of steroid pulse therapy.•The protocol of everolimus and low-dose tacrolimus extended-release successfully maintained the trough of each drug at a lower level, and it also kept renal function stable up to 1 year after transplantation.