Relationship between PTEN and Vascular Endothelial Growth Factor Expression in Non-Small Cell Lung Cancer.

Mee Sook Roh, Jae Ik Lee,Doo Kyung Yang,Soo Keol Lee,Hyuk Chan Kwon, Mi Kyoung Park, Ki Baek Hwang, Jin A Jung

Cancer research and treatment : official journal of Korean Cancer Association（2003）

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摘要

These findings demonstrate an inverse correlation between the expressions of PTEN and VEGF. It is possible that PTEN may repress VEGF expression, and modulate VEGF-mediated angiogenesis, which suggests further analysis of the complex phenomenon of neo-angiogenesis in NSCLC is essential.

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关键词

Angiogenesis,Chromosome 10,Non-small cell lung cancer,Vascular endothelial growth factor

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