Rif1 binds to G quadruplexes and suppresses replication over long distances

Yutaka Kanoh,Seiji Matsumoto,Rino Fukatsu,Naoko Kakusho,Nobuaki Kono,Claire Renard-Guillet,Koji Masuda,Keisuke Iida,Kazuo Nagasawa,Katsuhiko Shirahige,Hisao Masai

NATURE STRUCTURAL & MOLECULAR BIOLOGY（2015）

引用 127|浏览27

暂无评分

摘要

ChIP-seq, biochemical and in vivo assays show that Rif1 binds G-rich motifs that can form G-quadruplex structures, thus regulating firing of proximal and distal DNA replication origins in fission yeast.

查看译文

关键词

DNA,DNA replication,Life Sciences,general,Biochemistry,Protein Structure,Membrane Biology,Biological Microscopy

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要