Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric in silico ROCOCO trial.

Daniëlle B P Eekers,Erik Roelofs,Macarena Cubillos-Mesías, Charles Niël,Robert Jan Smeenk,Ann Hoeben,Andre W H Minken,Marlies Granzier,Geert O Janssens,Johannes H A M Kaanders,Philippe Lambin,Esther G C Troost

Acta oncologica (Stockholm, Sweden)（2019）

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摘要

The low dose volume to the majority of OARs was significantly reduced when using IMPT compared to VMAT. Whether this will lead to a significant reduction in neurocognitive decline and improved quality of life is to be determined in carefully designed future clinical trials.

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