BAFF-R and TACI expression on CD3+ T cells: Interplay among BAFF, APRIL and T helper cytokines profile in systemic lupus erythematosus.

•The TACI receptor is increased on CD3+ T cells of active SLE patients and correlates with IL-10 and IL-6.•BAFF serum levels correlate with disease activity in SLE.•APRIL serum levels are increased in SLE patients with renal activity and correlate with SLICC.•APRIL mainly associates with Th1 cytokines, whereas BAFF correlates with Th2 cytokine profile.•BAFF and APRIL could promote imbalance in Th1 and Th2 cytokines.