Long-chain polyunsaturated fatty acid biosynthesis and its response to cadmium exposure in silver pomfret.

Kai Liao,Zhaoshou Ran,Ran Meng,Jilin Xu,Jiayi Cao,Xiaorong Xu,Yajun Wang,Shanliang Xu,Xiaojun Yan

Aquatic Toxicology（2019）

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摘要

•Silver pomfret can biosynthesize DHA from endogenous EPA.•Cd exposure increases the brain-specific expression of genes required for DHA synthesis from EPA.•Pparα regulates LC-PUFA biosynthesis gene expression in response to Cd exposure.•Cd exposure reduces the DHA concentration and increases the malondialdehyde concentration in the brain of silver pomfret.

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关键词

ALA,Cd,DHA,Elovl,EPA,Fads,Hnf4α,LA,LC-PUFA,Lxrα,Pparα,Srebp1

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