Anti-glioma effect of intracranial vaccination with tumor cell lysate plus flagellin in mice.

Boqi Dong,Liying Wang,Shu Nie,Xin Li,Yue Xiao,Lei Yang,Xiuping Meng,Peiyan Zhao,Cuiyun Cui,Liqun Tu,Wenting Lu,Wei Sun,Yongli Yu

Vaccine（2018）

引用 6|浏览17

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摘要

•TCL plus flagellin prolong the survival of the GL261-bearing mice.•Flagellin assists the TCL to induce the anti-glioma immunity.•Intracranial administration of flagellin recruits T cells to brain.•Intracranial administration of flagellin induces proliferation of T cells.

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关键词

Tumor cell lysate,Flagellin,Vaccine,Adjuvant,Glioma

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