Neonatal ethanol exposure impairs long-term context memory formation and prefrontal immediate early gene expression in rats.

•In the CPFE, developmental alcohol exposure abolishes postshock and retention freezing.•Ethanol impairs prefrontal but not hippocampal gene expression during context exposure.•Ethanol exposure has no effect on freezing in standard contextual fear conditioning.•Evidence for prefrontal cognitive impairment in an animal model of FASD.