Arachidonic Acid Induces the Migration of MDA-MB-231 Cells by Activating Raft-associated Leukotriene B4 Receptors.

Atasi De Chatterjee,Debarshi Roy,Priscilla Guevara,Rituraj Pal,Mahesh Naryan,Sukla Roychowdhury,Siddhartha Das

Clinical cancer drugs（2018）

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摘要

Our results suggest that AA treatment activates the BLT1 receptor (present in membrane microdomains) and stimulates the synthesis of LTB production, which is likely to be associated with the migration of MDA-MB-231 cells.

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关键词

Breast cancer,MCF-7,MDA-MB-231,eicosanoids,leukotrienes,lipid rafts

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