A Highly Selective And Sensitive Fluorescent Probe For Simultaneously Distinguishing And Sequentially Detecting H2s And Various Thiol Species In Solution And In Live Cells

Dan Qiao,Tangliang Shen,Mengyuan Zhu,Xiao Liang,Lu Zhang,Zheng Yin,Binghe Wang,Luqing Shang

CHEMICAL COMMUNICATIONS（2018）

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摘要

A novel dual-channel fluorescent probe (NCR) based on differences in reactivity among H2S, Cys/Hcy, and GSH was rationally designed for simultaneously distinguishing and sequentially sensing H2S, Cys/Hcy, and GSH using two emission channels, which also demonstrated that NCR can be used for targeting mitochondria in mammalian cells.

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