A new polymer-based approach for in vivo transfection in postnatal brain.

C Di Scala,M Tessier,C Sapet,F Poulhes, F Sicard,O Zelphati,C Pellegrino

Journal of Neuroscience Methods（2019）

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摘要

•Transfection of neuronal cells in the postnatal rat brain.•Large volume-dependent diffusion scale in the 3-D axis.•Functional assay showing the potent efficacy in modifying large cell populations.

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关键词

Transfection,In vivo,Gene delivery,Non viral gene therapy,KCC2,Postnatal brain,Rattus norvegicus

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