Efficacy and Cardiotoxic Safety Profile of Raltitrexed in Fluoropyrimidines-Pretreated or High-Risk Cardiac Patients With GI Malignancies: Large Single-Center Experience.

Khurum Khan,Jayant K Rane,David Cunningham,Sheela Rao,David Watkins,Naureen Starling,Eleftheria Kalaitzaki,Martin Forster,Chiara Braconi,Nicola Valeri,Marco Gerlinger,Ian Chau

Clinical Colorectal Cancer（2019）

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摘要

A raltitrexed-based regimen is well-tolerated therapy with comparable efficacy to FPs in patients with GI malignancies with significant CV toxicities or risk factors.

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关键词

Capecitabine,Cardiotoxicity,Colorectal cancer,Gastroesophageal cancer,5-FU

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