Discovery of Pyrrolidine-Containing GPR40 Agonists: Stereochemistry Effects a Change in Binding Mode
Elizabeth A. Jurica,Ximao Wu,Kristin N. Williams,Andres S. Hernandez,David S. Nirschl,Richard A. Rampulla,Arvind Mathur,Min Zhou,Gary Cao,Chunshan Xie,Biji Jacob,Hong Cai,Tao Wang,Brian J. Murphy,Heng Liu,Carrie Xu,Lori K. Kunselman,Michael B. Hicks,Qin Sun,Dora M. Schnur,Doree F. Sitkoff,Elizabeth A. Dierks,Atsu Apedo, Douglas B. Moore,Kimberly A. Foster,Mary Ellen Cvijic,Reshma Panemangalore,Neil A. Flynn,Brad D. Maxwell,Yang Hong, Yuan Tian,Jason J. Wilkes,Bradley A. Zinker,Jean M. Whaley,Joel C. Barrish,Jeffrey A. Robl,William R. Ewing,Bruce A. Ellsworth Journal of Medicinal Chemistry（2017）
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