3D dynamic MRI of the vocal tract during natural speech.

Purpose: To develop and evaluate a technique for 3D dynamic MRI of the full vocal tract at high temporal resolution during natural speech. Methods: We demonstrate 2.4 x 2.4 x 5.8 mm(3) spatial resolution, 61-ms temporal resolution, and a 200 x 200 x 70 mm(3) FOV. The proposed method uses 3D gradient-echo imaging with a custom upper-airway coil, a minimum-phase slab excitation, stack-of-spirals readout, pseudo golden-angle view order in k(x)-k(y), linear Cartesian order along k(z), and spatiotemporal finite difference constrained reconstruction, with 13-fold acceleration. This technique is evaluated using in vivo vocal tract airway data from 2 healthy subjects acquired at 1.5T scanner, 1 with synchronized audio, with 2 tasks during production of natural speech, and via comparison with interleaved multislice 2D dynamic MRI. Results: This technique captured known dynamics of vocal tract articulators during natural speech tasks including tongue gestures during the production of consonants "s" and "l" and of consonant-vowel syllables, and was additionally consistent with 2D dynamic MRI. Coordination of lingual (tongue) movements for consonants is demonstrated via volume-of-interest analysis. Vocal tract area function dynamics revealed critical lingual constriction events along the length of the vocal tract for consonants and vowels. Conclusion: We demonstrate feasibility of 3D dynamic MRI of the full vocal tract, with spatiotemporal resolution adequate to visualize lingual movements for consonants and vocal tact shaping during natural productions of consonant-vowel syllables, without requiring multiple repetitions.