Quantifying the interactions between biomimetic biomaterials - collagen I, collagen IV, laminin 521 and cellulose nanofibrils - by colloidal probe microscopy.

Colloids and Surfaces B: Biointerfaces(2019)

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摘要
•Biomaterial-biomaterial interactions were quantified by colloidal probe microscopy.•The strongest adhesion was for self- and cross-interactions of Col IV and laminin-521.•CNF adhered very well to collagen, but poor adhesion to laminin was observed.•The results can support the development of new composites for tissue engineering.•The interactions between main proteins in extracellular matrix are better understood.
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关键词
Collagen,Laminin,Cellulose nanofibrils,Surface forces,Adhesion,AFM-colloidal probe technique
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