Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma.

Yoshinobu Shigekawa,Shinya Hayami,Masaki Ueno,Atsushi Miyamoto,Norihiko Suzaki,Manabu Kawai,Seiko Hirono,Ken-Ichi Okada,Ryuji Hamamoto,Hiroki Yamaue

Oncotarget（2018）

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摘要

Overexpression of KDM5B results in poor prognosis in HCC that especially derived from HBV/HCV. KDM5B appears to be an ideal target for the development of anti-cancer drugs.

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关键词

KDM5B/JARID1B,epigenetics,hepatocellular carcinoma (HCC),histone demethylase

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