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Discovery and Optimization of a Novel Series of Pyrazolyltetrahydropyran N-type Calcium Channel (cav 2.2) Blockers for the Treatment of Pain

Mark J. Wall,Nalin L. Subasinghe,Michael P. Winters,Mary Lou Lubin,Michael F. A. Finley,Ning Qin,Michael R. Brandt,Michael P. Neeper,Craig R. Schneider,Raymond W. Colburn,Christopher M. Flores,Zhihua Sui

Bioorganic & Medicinal Chemistry Letters（2018）

Cited 6|Views35
Key words
Pain,N-type calcium channel,Cav 2.2,Pyrazoles,CFA model,CCI model
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