Burkholderia Lata Infections From Intrinsically Contaminated Chlorhexidine Mouthwash, Australia, 2016

Lex E. X. Leong,Diana Lagana,Glen P. Carter,Qinning Wang,Kija Smith,Tim P. Stinear,David Shaw,Vitali Sintchenko,Steven L. Wesselingh,Ivan Bastian,Geraint B. Rogers

EMERGING INFECTIOUS DISEASES（2018）

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摘要

Burkholderia lata was isolated from 8 intensive care patients at 2 tertiary hospitals in Australia. Whole-genome sequencing demonstrated that clinical and environmental isolates originated from a batch of contaminated commercial chlorhexidine mouthwash. Genomic analysis identified efflux pump-encoding genes as potential facilitators of bacterial persistence within this biocide.

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Australia,Burkholderia lata,bacteria,chlorhexidine mouthwash,genome analysis,intensive care unit,nosocomial infections

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