Parsing protein sulfinic acid switches
NATURE CHEMICAL BIOLOGY（2018）
摘要
The proteome-wide application of a probe that selectively labels cysteine residues oxidized to the sulfinic acid form reveals the mammalian S -sulfinylome and uncovers novel substrates of the sulfinyl reductase sulfiredoxin, opening yet unexplored realms of cysteine-based redox regulation.
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关键词
Chemical tools,Enzymes,Post-translational modifications,Chemistry/Food Science,general,Biochemical Engineering,Biochemistry,Cell Biology,Bioorganic Chemistry
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