Update to RIFM fragrance ingredient safety assessment, 3-ethylhexahydro-2(3H)-benzofuranone, CAS Registry Number 54491-17-7

A. M. Api,D. Belsito, D. Botelho, M. Bruze,G. A. Burton, M. A. Cancellieri, H. Chon, M. L. Dagli, W. Dekant,C. Deodhar, A. D. Fryer, L. Jones,K. Joshi, M. Kumar,A. Lapczynski, M. Lavelle, I. Lee,D. C. Liebler, H. Moustakas, J. Muldoon, T. M. Penning, G. Ritacco, J. Romine,N. Sadekar,T. W. Schultz, D. Selechnik, F. Siddiqi,I. G. Sipes,G. Sullivan,Y. Thakkar,Y. Tokura

FOOD AND CHEMICAL TOXICOLOGY（2023）

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摘要

•3-Ethylhexahydro-2(3H)-benzofuranone, safety assessment based on RIFM's criteria.•Safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.

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