Patterns of Age- and Sex-Related Variations in Bone Mineral Density of Lumbar Spine and Total Femur: A Retrospective Diagnostic Laboratory-Based Study.

Our study highlighted the variation of BMD at different sites of body and higher vulnerability of spine for fragility fractures. Our study has shown a sharp decline in BMD among women during transition from 5 to 6 decade which signifies association of menopause with osteoporosis. Major limitation of the study is unavailability of clinical profiles of the subjects because of which it is difficult to ascertain whether BMD estimation was a diagnostic or screening procedure. In addition, study is conducted in diagnostic lab settings, due to which it is possible to overestimate prevalence of low BMD and osteoporosis by extrapolating these findings to the community.