A biological study establishing the endotoxin limit for in vitro proliferation of human mesenchymal stem cells.

Yusuke Nomura,Chie Fukui,Yuki Morishita,Yuji Haishima

Regenerative Therapy（2017）

引用 17|浏览3

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摘要

•Risk of endotoxin contamination in an hMSC culture system was quantified.•Endotoxin increased proliferative capacity of hMSCs.•SOD2 has similar effects of hMSC proliferation as endotoxin.•Lowest observed adverse effect level of endotoxin was determined as 0.1 ng/ml.

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关键词

Endotoxin limit,Regenerative medicine products,Human mesenchymal stem cells,Proliferative capacity,Superoxide dismutase

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